APOC1 antibody

Catalog No. ABIN113010

The Rabbit Polyclonal anti-APOC1 antibody (ABIN113010) specifically detects APOC1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for APOC1 antibody (ABIN113010)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-APOC1 Antibody

Specificity: The antibody recognizes Apo CI. No cross-reactions with Apo AI, Apo AII, Apo B-100, Apo CII, Apo CIII, and Apo E.

Purification: Human Apo-CI-Sepharose affinity column

Immunogen: Human Apo-CI

Application Details

Application Notes: Can be used for detection of Apo CI in plasma and lipoproteins, for immunoassay,immunoblot, enzyme conjugation, or biotinylation. Recommended dilutions: Immunoblot (1: 200-1: 5,000). ELISA (1: 5,000-1: 20,000). Successful use in immunohistochemistry on frozen sections was reported by someresearchers. As this detection method has not been verified by antibodies-online, theapplication was deleted from the database. This does not necessarily exclude the use insuch procedure.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL (OD280, E0.1% = 1.35)

Buffer: 75 mM PBS, 75 mM NaCl, pH 7.2 containig 1 mM EDTA and 0.02 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) -20 °C for longer.

Target Details for APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Alternative Name: Apolipoprotein C I (Apo CI)

Background: The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.Synonyms: Apo-CI, Ap °C-I, Ap °C1, Apolipoprotein C-I, Apolipoprotein C1

Gene ID: 341

NCBI Accession: NP_001636

UniProt: P02654

Pathways: Apoptosis