Chromogranin A antibody (N-Term)

Catalog No. ABIN113289

The Sheep Polyclonal anti-Chromogranin A antibody (ABIN113289) specifically detects Chromogranin A in EIA. The antibody is reactive with Human samples.

Quick Overview for Chromogranin A antibody (N-Term) (ABIN113289)

Target: Chromogranin A (CHGA)

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Chromogranin A antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-Chromogranin A Antibody

Binding Specificity: AA 1-15, N-Term

Sequence: L-P-V-N-S-P-M-N-K-G-D-T-E-V-M

Specificity: This antibody detects Chromogranin A.

Purification: Prepared by Ammonium Sulphate fractionation

Immunogen: Synthetic peptide corresponding to the amino acids 1 - 15 of the native molecule conjugated to Keyhole limpet Haemocyanin.

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 9.8 mg/mL

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Chromogranin A

Target: Chromogranin A (CHGA)

Alternative Name: Chromogranin A

Background: Chromogranin A (a protein of 439 amino acids which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.Synonyms: CHGA, CgA, Chromogranin-A, Pituitary secretory protein I, SP-I

Gene ID: 1113

NCBI Accession: NP_001266

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling