ITM2B antibody (N-Term)

Catalog No. ABIN113331

Product Details anti-ITM2B Antibody

Target: ITM2B (Integral Membrane Protein 2B (ITM2B))

Binding Specificity: N-Term

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This ITM2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Affinity chromatography.

Immunogen: Peptide coupled to carrier protein. Amino terminal sequence of BRI protein (ITM2B)

Application Details

Application Notes: Suitable for Western blot and not recommended for Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline, pH 7.2 with 0.09 % sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2-8 °C for one month or (following reconstitution in aliquots) at -20 °C for longer.

Target Details for ITM2B

Target: ITM2B (Integral Membrane Protein 2B (ITM2B))

Alternative Name: ITM2B (ITM2B Products)

Background: This antibody has been developed against the amino terminal sequence of BRI protein (ITM2B), a type-II single spanning transmembrane protein found in brain and other tissues. Mutation of the BRI gene with concomitant elongation of the carboxy terminus and its cleavage by the protease furin has been shown to lead to deposition of a protein fragment that may be involved in the pathogenesis of familial British dementia.Synonyms: BRI, BRI2, ITM2B, Integral membrane protein 2B, Transmembrane protein BRI

Gene ID: 9445

NCBI Accession: NP_068839

UniProt: Q9Y287