MCHR2 antibody (C-Term)

Catalog No. ABIN113335

This Chicken Polyclonal antibody specifically detects MCHR2 in IHC (fro). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MCHR2 antibody (C-Term) (ABIN113335)

Target: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This MCHR2 antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MCHR2 Antibody

Binding Specificity: C-Term

Sequence: TEKEINNMGN TLKSHF Remarks: The antibody was generated against the intracellu lar C-terminal sequence of the Human receptor.

Specificity: This antibody react with Mouse and Rat tissue as well. The staining pattern is extensive throughout the brain, and particularly striking in the ganglionic layer of the cerebellum.

Purification: Affinity Chromatography.

Immunogen: Peptide coupled to carrier protein. Antigen, Epitope: C-terminal portion of MCH-R2.

Application Details

Application Notes: Immunohistochemistry on Frozen Sections: 0.5-1 μg/mL (1/1000-1/2000). Recommended Positive Control: brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS pH 7.2 containing 0.09 % Sodium Azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Do not freeze working dilutions

Target Details for MCHR2

Target: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Alternative Name: MCHR2 / GPR145

Background: Melanin Concentrating Hormone Receptor type 2 (MCH-R2) is a G-protein coupled seven transmembrane receptor that shares considerable homology with MCH-R1. Like MCH-R1, it binds MCH with high affinity. However, reports indicate that signaling through this receptor is pertussis insensitive, contrary to MCH-R1.Synonyms: G-protein coupled receptor 145, GPRv17, MCH receptor 2, MCH-2R, MCH-R2, MCHR-2, Melanin-concentrating hormone receptor 2, SLT

Gene ID: 84539

NCBI Accession: NP_001035269

UniProt: Q969V1