HLA-ABC antibody
Quick Overview for HLA-ABC antibody (ABIN114528)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purification
- Affinity Chromatography on Protein G.
-
Immunogen
- Purified class I HLA complex.
-
Isotype
- IgG1
-
-
-
-
Application Notes
-
Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Reconstitution
- Restore in Double distillated water
-
Concentration
- 1.0 mg/mL
-
Buffer
- 0.01 M PBS, pH 7.2
-
Precaution of Use
- This product contains sodium azide : a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. 12 months from date of reconstitution.
-
Storage
- 4 °C
-
Storage Comment
- Prior to reconstitution store at +4 °C. Following reconstitution store at +4 °C. DO NOT FREEZE. This product should be stored undiluted.
-
-
- HLA-ABC
-
Alternative Name
- HLA Class I ABC
-
Background
- Human leukocyte antigen (HLA) is the antigen binding, membrane bound α chain of major histocompatibility complex I (MHC1). While the small β chain is the invariable beta 2 microglobulin, the α chain has three major isoforms (HLA-A, HLA-B, HLA-C) that are encoding by different loci on chromosome 6 and each of the isoforms has a highly variable region that resembles Fab on immunoglobulin. The HLA-ABC antibody reacts with a common epitope shared by HLA-A, HLAB and HLA-C.Synonyms: HLA Class 2 ABC, Human Leukocyte antigen class I ABC, MHC class I ABC, Major Histocompatibility complex class I
-
Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
-