S100B antibody

Catalog No. ABIN115345

This Rabbit Polyclonal antibody specifically detects S100B in IHC (p) and IHC (fro). It exhibits reactivity toward Human and Cow.

Quick Overview for S100B antibody (ABIN115345)

Target: S100B (S100 Calcium Binding Protein B (S100B))

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-S100B Antibody

Specificity: This antibody reacts with cow S-100 protein A and B.
Cellular Localization: Cytoplasmic

Purification: Purified

Immunogen: Affinity purified S-100 protein isolated from cow brain.

Application Details

Application Notes: Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 200 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Melanoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: containing sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for S100B

Target: S100B (S100 Calcium Binding Protein B (S100B))

Alternative Name: S100B

Background: The Antibody shows strong cross-reactivity with human S-100 A and B. In the brain, it labels glial and ependymal cells. Melanocytes and Langerhans cells of the skin stain positive with this antibody.Synonyms: Astrocyte Marker, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 beta, S100 calcium-binding protein B

Gene ID: 525716

NCBI Accession: NP_001029727

UniProt: P02638

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins