Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MSTN antibody

MSTN Reactivity: Human EIA Host: Chicken Polyclonal unconjugated
Catalog No. ABIN115510
  • Target See all MSTN Antibodies
    MSTN (Myostatin (MSTN))
    Reactivity
    • 75
    • 49
    • 43
    • 18
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 88
    • 14
    • 5
    • 3
    • 3
    • 1
    • 1
    Chicken
    Clonality
    • 98
    • 17
    Polyclonal
    Conjugate
    • 54
    • 21
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MSTN antibody is un-conjugated
    Application
    • 97
    • 47
    • 46
    • 26
    • 26
    • 14
    • 13
    • 9
    • 9
    • 6
    • 5
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Sequence
    Total 248 AA. MW: 28 kDa (calculated ). 243 AA of recombinan t human Myostatin Propeptide and 5 extra AA: MGNENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRRKLN Remarks: The amino acid sequence of the recombinan t Human Myostatin Propeptide is 100% homologous with the amino acid sequence of the Human Myostatin Propeptide without signaling sequence.
    Specificity
    The recombinant human myostatin propeptide is 100 % homologous with the human serum myostatin propeptide.
    Purification
    Immunoaffinity chromatography.
    Immunogen
    Recombinant human myostatin propeptide from E. coli.
  • Application Notes
    Suitable for ELISA: Titer is defined by indirect ELISA, it is: > 1/100,000 for antibodyconcentration 1 mg/mL, 25 ng of antigen are coated per well, and is then defined at a pointof maximal decrease of the titration curve.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Add 0.05 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
    Concentration
    1.0 mg/mL
    Buffer
    0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2 containing no preservatives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing. Dilute only prior to immediate use.
    Storage
    -20 °C
    Storage Comment
    Store (in aliquots) at -20° C or below.
  • Target
    MSTN (Myostatin (MSTN))
    Alternative Name
    Myostatin (MSTN Products)
    Synonyms
    GDF-8 antibody, GDF8 antibody, gdf8 antibody, mstn antibody, zgc:109749 antibody, Gdf8 antibody, NV13143 antibody, MSLHP antibody, Cmpt antibody, myostatin antibody, myostatin b antibody, growth/differentiation factor 8 antibody, MSTN antibody, mstnb antibody, LOC5577632 antibody, BRAFLDRAFT_290840 antibody, Mstn antibody, mstn antibody
    Background
    Myostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70 % ) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.Synonyms: GDF-8, GDF8, Growth differentiation factor 8, MSTN
    Gene ID
    2660
    NCBI Accession
    NP_005250
    UniProt
    O14793
You are here:
Support