Neurturin antibody

Catalog No. ABIN116221

Product Details anti-Neurturin Antibody

Target: Neurturin (NRTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurturin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificity: This antibody reacts with Human Neurturin.

Purification: Affinity chromatography.

Immunogen: Highly pure (>98%) recombinant hNeurturin.

Application Details

Application Notes: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhNeurturin (50.00 ng/mL), a concentration of 0.5-0.75 μg/mL of this antibody is required. ELISA: To detect hNeurturin by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hNeurturinWestern Blot: To detect hNeurturin by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hNeurturin is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Target Details for Neurturin

Target: Neurturin (NRTN)

Alternative Name: Neurturin (NRTN Products)

Synonyms: NRTN antibody, NTN antibody, neurturin antibody, NRTN antibody, Nrtn antibody

Background: Human Neurturin (NTN) and Human GDNF comprise a family of TGF-beta related neurotrophic factor which have trophic influences on a variety of neuronal populations. Neurturin promotes the survival of certain sympathetic and sensory neurins through interaction with distinct set of GDNF-like receptors.Synonyms: NRTN

Gene ID: 4902

NCBI Accession: NP_004549

UniProt: Q99748