CCL23 antibody

Catalog No. ABIN116289

Product Details anti-CCL23 Antibody

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL23 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificity: Macrophage Inflammatory Protein-3 (MIP-3) (MPIF-1)

Purification: Affinity chromatography.

Immunogen: Highly pure (>98%) recombinant hMIP-3.

Application Details

Application Notes: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhMIP-3 (100.0 ng/mL), a concentration of 2.0-4.0 μg/mL of this antibody is required. ELISA: To detect hMIP-3 by direct ELISA (using 100l/well antibody solution) aconcentration of at least 0.5g/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of0.2-0.4 ng/well of recombinant hMIP-3. Western Blot: To detect hMIP-3 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hMIP-3 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Target Details for CCL23

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Alternative Name: MIP3 / CCL23 (CCL23 Products)

Synonyms: CK-BETA-8 antibody, CKb8 antibody, Ckb-8 antibody, Ckb-8-1 antibody, MIP-3 antibody, MIP3 antibody, MPIF-1 antibody, SCYA23 antibody, hmrp-2a antibody, C-C motif chemokine 23 antibody, C-C motif chemokine ligand 23 antibody, chemokine (C-C motif) ligand 23 antibody, LOC508666 antibody, CCL23 antibody

Background: Macrophage Inflammatory Protein 3 (MIP3) is chemotactic for monocytes, resting T-lymphocytes, and neutrophils. It inhibits proliferation of myeloid progenitor cells and is highly expressed in adult lung, liver, skeletal muscle and pancreas. There are moderate levels of MIP3 in fetal liver, adult bone marrow and placenta. MIP3 belongs to the intercrine beta family (small cytokine c-c) (chemokine c-c).Synonyms: C-C motif chemokine 23, CCL-23, CK-beta-8, CKB-8, MIP-3, MPIF1, Macrophage inflammatory protein 3, Myeloid progenitor inhibitory factor 1, SCYA23, Small-inducible cytokine A23

Gene ID: 6368

NCBI Accession: NP_005055

UniProt: P55773