TIM3 antibody

Catalog No. ABIN1169016

This Rat Monoclonal antibody specifically detects TIM3 in FACS and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for TIM3 antibody (ABIN1169016)

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TIM3 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: TI 142F

Product Details anti-TIM3 Antibody

Purpose: anti-Tim-3 (mouse), mAb (TI 142F)

Specificity: Recognizes mouse Tim-3.

Characteristics: Monoclonal Antibody. Recognizes mouse Tim-3. Isotype: Rat IgG2akappa. Clone: TI 142F. Applications: ELISA, FACS. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Tim-3 is a Th1-specific cell surface protein. It is expressed selectively by differentiated CD4+Th1 and CD8+Tc1 cells, but is absent on CD4+Th2 and CD8+ Tc2 cells. The Tim gene family has an important role in the regulation of autoimmunity and allergies.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse Tim-3.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Alternative Name: Tim-3

Target Type: Virus

Background:

Alternate Names/Synonyms: TIM3, TIMD3, Hepatitis A Virus Cellular Receptor 2, HAVcr-2, T Cell Immunoglobulin and Mucin Domain-containing Protein 3

Product Description: Tim-3 is a Th1-specific cell surface protein. It is expressed selectively by differentiated CD4+Th1 and CD8+Tc1 cells, but is absent on CD4+Th2 and CD8+ Tc2 cells. The Tim gene family has an important role in the regulation of autoimmunity and allergies.

UniProt: Q8VIM0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints