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TNFRSF18 antibody
TNFRSF18
Reactivity: Mouse
FACS, ELISA
Host: Rat
Monoclonal
MGIT 02
unconjugated
Product Details anti-TNFRSF18 Antibody
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Target
See all TNFRSF18 Antibodies
TNFRSF18
(Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
Reactivity
All reactivities for TNFRSF18 antibodies
Mouse
Host
All hosts for TNFRSF18 antibodies
Rat
Clonality
All clonalities for TNFRSF18 antibodies
Monoclonal
Conjugate
All conjugates for TNFRSF18 antibodies
This TNFRSF18 antibody is un-conjugated
Application
All applications for TNFRSF18 antibodies
Flow Cytometry (FACS), ELISA
Specificity
Recognizes mouse GITR.
Cross-Reactivity
Mouse (Murine)
No Cross-Reactivity
Human
Cross-Reactivity (Details)
Does not cross-react with human GITR.
Sterility
0.2 μm filtered
Immunogen
Recombinant mouse GITR.
Clone
MGIT 02
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Preservative
Without preservative
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Target Details for TNFRSF18
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Target
TNFRSF18
(Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
Alternative Name
GITR (TNFRSF18 Products )
Synonyms
GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
Background
GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.
UniProt
O35714
Pathways
Cancer Immune Checkpoints
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