TNFRSF18 antibody

Catalog No. ABIN1169036

The Rat Monoclonal anti-TNFRSF18 antibody is suitable to detect TNFRSF18 in samples from Mouse. It has been validated for FACS and ELISA.

Quick Overview for TNFRSF18 antibody (ABIN1169036)

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TNFRSF18 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: MGIT 02

Product Details anti-TNFRSF18 Antibody

Specificity: Recognizes mouse GITR.

Cross-Reactivity: Mouse (Murine)

No Cross-Reactivity: Human

Cross-Reactivity (Details): Does not cross-react with human GITR.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse GITR.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Alternative Name: GITR

Background: GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.

UniProt: O35714

Pathways: Cancer Immune Checkpoints