GPX3 antibody

Catalog No. ABIN1169115

Product Details anti-GPX3 Antibody

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Recognizes mouse GPX3. Detects a band of ~20-27 kDa by Western blot.

Cross-Reactivity: Mouse (Murine)

Cross-Reactivity (Details): Weakly cross-reacts with human GPX3.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse GPX3.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details for GPX3

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Alternative Name: GPX3 (GPX3 Products)

Synonyms: GPX3 antibody, DKFZp469D1932 antibody, AA960521 antibody, EGPx antibody, GPx antibody, GSHPx-3 antibody, GSHPx-P antibody, GPx-3 antibody, GPx-P antibody, Gpxp antibody, glutathione peroxidase 3 antibody, gpx3 antibody, GPX3 antibody, Gpx3 antibody

Background: Glutathione peroxidase 3 (GPX3, GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.

UniProt: P46412

Pathways: Thyroid Hormone Synthesis