GPX3 antibody
Quick Overview for GPX3 antibody (ABIN1169115)
Target
See all GPX3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes mouse GPX3. Detects a band of ~20-27 kDa by Western blot.
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Cross-Reactivity
- Mouse (Murine)
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Cross-Reactivity (Details)
- Weakly cross-reacts with human GPX3.
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Sterility
- 0.2 μm filtered
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Immunogen
- Recombinant mouse GPX3.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Preservative
- Without preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Expiry Date
- 6 months
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- GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))
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Alternative Name
- GPX3
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Background
- Glutathione peroxidase 3 (GPX3, GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.
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UniProt
- P46412
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Pathways
- Thyroid Hormone Synthesis
Target
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