GPX3 antibody

Catalog No. ABIN1169115

The Rabbit Polyclonal anti-GPX3 antibody (ABIN1169115) specifically detects GPX3 in WB and ELISA. The antibody is reactive with Mouse samples.

Quick Overview for GPX3 antibody (ABIN1169115)

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GPX3 Antibody

Purpose: anti-GPX3, pAb

Specificity: Recognizes mouse GPX3. Detects a band of ~20-27 kDa by Western blot. Weakly cross-reacts with human GPX3.

Cross-Reactivity (Details): Weakly cross-reacts with human GPX3.

Characteristics: Polyclonal Antibody. Recognizes mouse GPX3. Detects a band of ~20-27 kDa by Western blot. Weakly cross-reacts with human GPX3. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Glutathione peroxidase 3 (GPX3, GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse GPX3.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details for GPX3

Target: GPX3 (Glutathione Peroxidase 3 (Plasma) (GPX3))

Alternative Name: GPX3

Background:

Alternate Names/Synonyms: Glutathione Peroxidase 3

Product Description: Glutathione peroxidase 3 (GPX3, GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.

UniProt: P46412

Pathways: Thyroid Hormone Synthesis