SENP2 antibody (Catalytic Domain)
Quick Overview for SENP2 antibody (Catalytic Domain) (ABIN1169125)
Target
See all SENP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Catalytic Domain
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Purpose
- anti-SENP2 (mouse), pAb
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Specificity
- Recognizes mouse SENP2. Detects a band of ~26 kDa (rec) and ~68 kDa in mouse brain lysate by Western blot.
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Characteristics
- Polyclonal Antibody. Recognizes mouse SENP2. Detects a band of ~26 kDa (rec) and ~68 kDa in mouse brain lysate by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Downregulates CTNNB1 levels and thereby modulates the Wnt pathway.
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Sterility
- 0.2 μm filtered
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Immunogen
- Recombinant mouse SENP2 (catalytic domain).
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Preservative
- Without preservative
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Handling Advice
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Expiry Date
- 6 months
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- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
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Alternative Name
- SENP2
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Background
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Alternate Names/Synonyms: Axam2, Smt3ip2, Sentrin-specific Protease 2
Product Description: SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Downregulates CTNNB1 levels and thereby modulates the Wnt pathway.
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UniProt
- Q91ZX6
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Pathways
- Chromatin Binding
Target
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