ADIPOQ antibody

Catalog No. ABIN1169211

Cited in 4+ publications. The Mouse Monoclonal anti-ADIPOQ antibody (Clone HADI 773) (ABIN1169211) specifically detects ADIPOQ in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for ADIPOQ antibody (ABIN1169211)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADIPOQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: HADI 773

Product Details anti-ADIPOQ Antibody

Purpose: anti-Adiponectin (human), mAb (HADI 773)

Specificity: Recognizes human adiponectin. Detects a band of ~30 kDa by Western blot. Cross-reactivity with other species not tested.

Cross-Reactivity (Details): Cross-reactivity with other species not tested.

Characteristics: Monoclonal Antibody. Recognizes human adiponectin. Detects a band of ~30 kDa by Western blot. Cross-reactivity with other species not tested. Isotype: Mouse IgG1kappa. Clone: HADI 773. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human adiponectin.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

References for anti-ADIPOQ antibody (ABIN1169211)

Barresi, Grosso, Giuffrè, Tuccari, Barresi: "The expression of adiponectin receptors Adipo-R1 and Adipo-R2 is associated with an intestinal histotype and longer survival in gastric carcinoma." in: Journal of clinical pathology, Vol. 62, Issue 8, pp. 705-9, (2009) (PubMed).

Achard, Boullu-Ciocca, Desbriere, Nguyen, Grino: "Renin receptor expression in human adipose tissue." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 292, Issue 1, pp. R274-82, (2007) (PubMed).

Corbetta, Bulfamante, Cortelazzi, Barresi, Cetin, Mantovani, Bondioni, Beck-Peccoz, Spada: "Adiponectin expression in human fetal tissues during mid- and late gestation." in: The Journal of clinical endocrinology and metabolism, Vol. 90, Issue 4, pp. 2397-402, (2005) (PubMed).

Lee, Lee, Cho, Moon, Jung, Park, Park, Youn, Lee, Park, Shin: "Genetic association study of adiponectin polymorphisms with risk of Type 2 diabetes mellitus in Korean population." in: Diabetic medicine : a journal of the British Diabetic Association, Vol. 22, Issue 5, pp. 569-75, (2005) (PubMed).

Target Details for ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Alternative Name: Adiponectin

Background:

Alternate Names/Synonyms: ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30 kDa

Product Description: ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.

UniProt: Q15848