ADIPOQ antibody

Catalog No. ABIN1169212

This Mouse Monoclonal antibody specifically detects ADIPOQ in WB, ELISA and IP. It exhibits reactivity toward Mouse.It has been mentioned in 1 publication

Quick Overview for ADIPOQ antibody (ABIN1169212)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADIPOQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Clone: MADI 1147

Product Details anti-ADIPOQ Antibody

Purpose: anti-Adiponectin (mouse), mAb (MADI 1147)

Specificity: Recognizes mouse adiponectin. Detects a band of ~30 kDa by Western blot. Weakly cross-reacts with human and rat adiponectin.

Cross-Reactivity (Details): Weakly cross-reacts with human and rat adiponectin.

Characteristics: Monoclonal Antibody. Recognizes mouse adiponectin. Detects a band of ~30 kDa by Western blot. Weakly cross-reacts with human and rat adiponectin. Isotype: Mouse IgG1kappa. Clone: MADI 1147. Applications: ELISA, IP, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse adiponectin.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

References for anti-ADIPOQ antibody (ABIN1169212)

Sautin, Nakagawa, Zharikov, Johnson: "Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress." in: American journal of physiology. Cell physiology, Vol. 293, Issue 2, pp. C584-96, (2007) (PubMed).

Target Details for ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Alternative Name: Adiponectin

Background:

Alternate Names/Synonyms: ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30 kDa

Product Description: ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.

UniProt: Q60994