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DLL4 antibody (Extracellular Domain)

This Mouse Monoclonal antibody specifically detects DLL4 in WB and ELISA. It exhibits reactivity toward Human.
Catalog No. ABIN1169263

Quick Overview for DLL4 antibody (Extracellular Domain) (ABIN1169263)

Target

See all DLL4 Antibodies
DLL4 (delta-Like 4 (DLL4))

Reactivity

  • 57
  • 40
  • 19
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Host

  • 64
  • 16
  • 9
  • 3
  • 1
Mouse

Clonality

  • 65
  • 27
  • 1
Monoclonal

Conjugate

  • 58
  • 9
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DLL4 antibody is un-conjugated

Application

  • 48
  • 33
  • 22
  • 15
  • 13
  • 13
  • 11
  • 10
  • 9
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA

Clone

DL86-3AG
  • Binding Specificity

    • 15
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    Specificity

    Recognizes human DLL4.

    Cross-Reactivity

    Human

    Sterility

    0.2 μm filtered

    Immunogen

    Recombinant human DLL4 (extracellular domain).

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

    Preservative

    Without preservative

    Storage

    4 °C,-20 °C

    Storage Comment

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    Expiry Date

    12 months
  • Target

    DLL4 (delta-Like 4 (DLL4))

    Alternative Name

    DLL4

    Background

    The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

    UniProt

    Q9NR61

    Pathways

    Notch Signaling
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