ANGPTL7 antibody (Coiled coil domain)

Catalog No. ABIN1169278

This Rabbit Polyclonal antibody specifically detects ANGPTL7 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ANGPTL7 antibody (Coiled coil domain) (ABIN1169278)

Target: ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANGPTL7 Antibody

Binding Specificity: Coiled coil domain

Purpose: anti-ANGPTL7 (coiled-coil domain) (human), pAb

Specificity: Recognizes the coiled-coil domain of human ANGPTL7 and the ANGPTL7 full length protein. Weakly cross-reacts with the coiled-coil domains of human ANGPTL2, ANGPTL3, ANGPTL4 and ANGPTL5. Weakly cross-reacts with ANGPTL6 and ANGPTL3 full length protein. Does not cross-react with the fibrinogen like domain of ANGPTL7.

Cross-Reactivity (Details): Weakly cross-reacts with ANGPTL6 and ANGPTL3 full length protein. Does not cross-react with the fibrinogen like domain of ANGPTL7.

Characteristics: Polyclonal Antibody. Recognizes the coiled-coil domain of human ANGPTL7 and the ANGPTL7 full length protein. Weakly cross-reacts with the coiled-coil domains of human ANGPTL2, ANGPTL3, ANGPTL4 and ANGPTL5. Weakly cross-reacts with ANGPTL6 and ANGPTL3 full length protein. Does not cross-react with the fibrinogen like domain of ANGPTL7. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.

Sterility: 0.2 μm filtered

Immunogen: Coiled-coil domain of recombinant human ANGPTL7.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Preservative: Without preservative

Handling Advice: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details for ANGPTL7

Target: ANGPTL7 (Angiopoietin-Like 7 (ANGPTL7))

Alternative Name: ANGPTL7

Background:

Alternate Names/Synonyms: Angiopoietin-like Protein 7, Cornea-derived Transcript 6 Protein

Product Description: ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.

UniProt: O43827