IL1RL1 antibody
Quick Overview for IL1RL1 antibody (ABIN1169348)
Target
See all IL1RL1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- anti-ST2 (human), mAb (ST33868)
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Specificity
- Recognizes human ST2.
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Characteristics
- Monoclonal Antibody. Recognizes human ST2. Isotype: Mouse IgG1kappa. Clone: ST33868. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
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Sterility
- 0.2 μm filtered
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Immunogen
- Recombinant human soluble ST2.
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Isotype
- IgG1 kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Preservative
- Without preservative
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Handling Advice
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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Expiry Date
- 12 months
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- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
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Alternative Name
- ST2
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Background
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Alternate Names/Synonyms: Interleukin-1 Receptor-like 1, IL-1 Receptor-like 1, IL1RL1, IL-33 Receptor, Interleukin-33 Receptor
Product Description: The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
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UniProt
- Q01638
Target
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