Resistin antibody
Quick Overview for Resistin antibody (ABIN1169370)
Target
See all Resistin (RETN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes human resistin. Detects a band of ~10 kDa by Western blot.
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Cross-Reactivity
- Human
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Cross-Reactivity (Details)
- Weakly cross-reacts with mouse resistin.
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Sterility
- 0.2 μm filtered
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Immunogen
- Recombinant human resistin.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Preservative
- Without preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Expiry Date
- 6 months
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: "Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans." in: Diabetologia, Vol. 47, Issue 3, pp. 559-65, (2004) (PubMed).
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- Resistin (RETN)
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Alternative Name
- Resistin
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Background
- The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
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UniProt
- Q9HD89
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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