ACE2 antibody (Angiotensin I Converting Enzyme 2)

Details for Product anti-ACE2 Antibody No. ABIN1169446
Antigen
Reactivity
Human
296
76
51
19
2
2
2
2
1
1
Host
Rabbit
256
57
4
Clonality
Polyclonal
Conjugate
This ACE2 antibody is un-conjugated
30
14
10
9
9
8
3
3
3
3
3
3
3
2
1
1
1
1
Application
ELISA, Western Blotting (WB)
268
155
117
63
52
13
13
10
7
6
4
4
3
1
1
Options
Immunogen Recombinant human ACE2.
Specificity Recognizes human ACE2. Detects a band of ~90 kDa by Western blot.
Cross-Reactivity Human
Sterility 0.2 μm filtered
Antigen
Alternative Name ACE2 (ACE2 Antibody Abstract)
Background ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
UniProt Q9BYF1
Pathways ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Preservative Without preservative
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.
Expiry Date 6 months
Supplier Images
Image no. 1 for anti-Angiotensin I Converting Enzyme 2 (ACE2) antibody (ABIN1169446) Western blot analysis using anti-ACE2 (human), pAb at 1:2'000 dilution. 1: Human ACE...
Product cited in: Beniac, deVarennes, Andonov, He, Booth: "Conformational reorganization of the SARS coronavirus spike following receptor binding: implications for membrane fusion." in: PLoS ONE, Vol. 2, Issue 10, pp. e1082, 2007 (PubMed).