ITGAL antibody

Catalog No. ABIN1177317

The Mouse Monoclonal anti-ITGAL antibody (Clone HI111) (ABIN1177317) specifically detects ITGAL in FACS, Func and IHC (fro). The antibody is reactive with Human, Dog and Rabbit samples.

Quick Overview for ITGAL antibody (ABIN1177317)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human, Dog, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: HI111

Product Details anti-ITGAL Antibody

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility: 0.2 μm filtered

Endotoxin Level: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: CD11a

Background: The HI111 monoclonal antibody specifically binds to the 180 kDa integrin alpha chain. This type I transmembrane glycoprotein associates with CD18 (integrin beta2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50).
Synonyms: LFA-1alpha, Lymphocyte (Leukocyte) function-associated antigen 1 alpha chain, ITGAL

Pathways: Activated T Cell Proliferation, Integrin Complex