No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative
Azide free
Storage
4 °C
Storage Comment
Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Target
ITGA5
(Integrin, alpha 5 (ITGA5))
Alternative Name
CD49e
Background
Reacts with the alpha5 integrin, a dimer of 135/25 kDa, that associates with beta1 integrin (CD29) to form VLA-5, a well-established fibronectin receptor that is expressed on many cell types, including fibroblasts, endothelial cells, epithelial cells, platelets, peripheral T cells, the myeloid cell line U937, K562 and some melanoma cell lines. This clone inhibits alpha5beta1/ligand binding, and is useful for studies of the expression and function of this integrin. Synonyms: Integrin alpha5 Chain