RNF2 antibody (AA 189-201)

Catalog No. ABIN117940

This Goat Polyclonal antibody specifically detects RNF2 in WB, IF, IHC (p) and EIA. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken, Frog, Orang-Utan and Chimpanzee.

Quick Overview for RNF2 antibody (AA 189-201) (ABIN117940)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken, Frog, Orang-Utan, Chimpanzee

Host: Goat

Clonality: Polyclonal

Conjugate: This RNF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-RNF2 Antibody

Binding Specificity: AA 189-201

Sequence: 1 msqavqtngt qplsktwels lyelqrtpqe aitdgleivv sprslhselm cpicldmlkn 61 tmttkeclhr fcadciital rsgnkecptc rkklvskrsl rpdpnfdali skiypsrdey 121 eahqervlar inkhnnqqal shsieeglki qamnrlqrgk kqqiengsga edngdsshcs 181 nasthsnqea gpsnkrtkts ddsgleldnn naamaidpvm dgaseielvf rphptlmekd 241 dsaqtryikt sgnatvdhls kylavrlale elrskgesnq mnldtasekq ytiyiatasg 301 qftvlngsfs lelvsekywk vnkpmelyya ptkehk

Specificity: This antibody detects RING1B.

Cross-Reactivity (Details): Species reactivity (expected):Zebrafish.
Species reactivity (tested):Human, Chimpanzee, Orangutan, Mouse, Rrat, Dog, Bovine, Frog and Chicken.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding aa 189-201 of Human RING1B protein

Application Details

Application Notes: ELISA: 1/5,000-1/25,000. Western blot: 1/500-1/2,000. Expect a band approximately 38 kDa in size corresponding toRING1B by in the appropriate cell lysate or extract. Immunofluorescence.

Restrictions: For Research Use only

Handling

Concentration: 1.2 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 as buffer and 0.01 % (w/v) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: RNF2

Background: RING1B (also known as BAP1, DING, Polycomb-M33 interacting protein Ring1B, Ring finger protein 1b, Ring finger protein 2 and RNF2) is one of the PcG proteins. The polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), a ubiquitin-conjugating enzyme that possesses ubiquitin ligase activity.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B

Gene ID: 6045

NCBI Accession: NP_009143

UniProt: Q99496