CD57 antibody (FITC)

Catalog No. ABIN118743

This anti-CD57 antibody is a Mouse Monoclonal antibody detecting CD57 in FACS. Suitable for Human.

Quick Overview for CD57 antibody (FITC) (ABIN118743)

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD57 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: TB01

Product Details anti-CD57 Antibody (FITC)

Purification: Ion exchange chromatography

Immunogen: Human neuroblastoma cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3.X63.Ag8653 myeloma cell line.

Isotype: IgM

Application Details

Application Notes: Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD57

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Alternative Name: CD57 / HNK1

Background: CD57 recognizes a (Mr 100-110 kDa) oligosaccharide antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20 % of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60 %) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.Synonyms: HNK-1, LEU7, NK-1, NK-Cell marker, NK1

Gene ID: 27087

UniProt: Q9P2W7

Pathways: Glycosaminoglycan Metabolic Process