HLA-ABC antibody (HRP)

Catalog No. ABIN118898

The Mouse Monoclonal anti-HLA-ABC antibody has been validated for IHC (fro). It is suitable to detect HLA-ABC in samples from Human, Cow, Cat, Monkey and Primate. There are 3+ publications available.

Quick Overview for HLA-ABC antibody (HRP) (ABIN118898)

Target: HLA-ABC

Reactivity: Human, Cow, Cat, Monkey, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLA-ABC antibody is conjugated to HRP

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: W6-32

Product Details anti-HLA-ABC Antibody (HRP)

Purification: Affinity chromatography on Protein G

Immunogen: Purified human tonsil lymphocyte membranes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1/1-Ag4.1 myeloma cell line.

Isotype: IgG2a

Application Details

Application Notes: Immunhistochemistry on frozen sections. Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.01 % Thiomerosal

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HLA-ABC antibody (HRP) (ABIN118898)

Stern, Goldman, Hatasaka, Mackenzie, Surrey, Racowsky,: "Optimizing the number of cleavage stage embryos to transfer on day 3 in women 38 years of age and older: a Society for Assisted Reproductive Technology database study." in: Fertility and sterility, (2008) (PubMed).

Mayr, Bund, Schlee, Moosmann, Kofler, Hallek, Wendtner: "Fibromodulin as a novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8+ autologous T lymphocytes." in: Blood, Vol. 105, Issue 4, pp. 1566-73, (2005) (PubMed).

Mayr, Kofler, Büning, Bund, Hallek, Wendtner: "Transduction of CLL cells by CD40 ligand enhances an antigen-specific immune recognition by autologous T cells." in: Blood, Vol. 106, Issue 9, pp. 3223-6, (2005) (PubMed).

Target Details for HLA-ABC

Target: HLA-ABC

Alternative Name: HLA Class I ABC

Background: Synonyms: HLA Class 2 ABC, Human Leukocyte antigen class I ABC, MHC class I ABC, Major Histocompatibility complex class I

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints