MME antibody

Catalog No. ABIN119107

This Mouse Monoclonal antibody specifically detects MME in FACS, WB, IP and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for MME antibody (ABIN119107)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SN5c

Product Details anti-MME Antibody

Specificity: This antibody recognises the CD10 cell surface antigen.

Purification: Affinity chromatography on Protein G

Immunogen: Partially purified cell membrane antigens from fresh leukemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse PS/NS1/1-Ag4-1 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow cytometry. Immunoprecipitation. Immunohistochemistry on frozen sections. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10 / Neprilysin

Target Type: Chemical

Background: CD10 is a 100kD glycoprotein expressed by acute lymphoblastic leukaemia cells and by peripheral blood granulocytes. CD10 is also known as the Common Acute Lymphoblastic Leukaemia Antigen (CALLA).Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11

Gene ID: 4311

NCBI Accession: NP_000893

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration