CD236/GYPC antibody (Cytoplasmic Domain)

Catalog No. ABIN119181

The Mouse Monoclonal anti-CD236/GYPC antibody (Clone BRIC100) (ABIN119181) specifically detects CD236/GYPC in WB, IP and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for CD236/GYPC antibody (Cytoplasmic Domain) (ABIN119181)

Target: CD236/GYPC (GYPC) (Glycophorin C (GYPC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD236/GYPC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: BRIC100

Product Details anti-CD236/GYPC Antibody

Binding Specificity: Cytoplasmic Domain

Specificity: This antibody recognises a 17 amino acid residue within the cytoplasmic domain of glycophorin C (GPC), which has recently been designated CD236.

Purification: Purified

Immunogen: Synthetic peptide corresponding to amino acids in the cytoplasmic domain of GPC. Spleen cells from immunised Balb/c mice were fused with cells of the myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Western Blot. Immunoprecipitation. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD236/GYPC

Target: CD236/GYPC (GYPC) (Glycophorin C (GYPC))

Alternative Name: CD236 / GYPC

Background: Glycophorin C (CD236) is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin C plays an important role in regulating the stability of red cells.Synonyms: GLPC, GPC, Glycoconnectin, Glycophorin-D, Glycoprotein beta, PAS-2', Sialoglycoprotein D

Gene ID: 2995

NCBI Accession: NP_002092

UniProt: P04921