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HLA-ABC antibody

This anti-HLA-ABC antibody is a Rat Monoclonal antibody detecting HLA-ABC in FACS, IP, IHC (fro), IF and Func. Suitable for Human.
Catalog No. ABIN119778

Quick Overview for HLA-ABC antibody (ABIN119778)

Target

See all HLA-ABC Antibodies
HLA-ABC

Reactivity

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Human

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This HLA-ABC antibody is un-conjugated

Application

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Functional Studies (Func)

Clone

YTH862-2
  • Purification

    Affinity Chromatography on Protein G

    Immunogen

    PHA activated Human peripheral blood lymphocytes. Remarks: Spleen cells from immunised DA rats were fused with cells of the rat Y3 myeloma cell line.

    Isotype

    IgG2b
  • Application Notes

    Immunoprecipitation (1) Immunohistochemistry on frozen sections Flow Cytometry (1/50 - 1/100, use 10 μL of the suggested working dilution to label 106 cells in 100 μL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the reconstituted antibody at 2-8 °C for one month (add 0.09% Sodium Azide) or at -20 °C for longer.
  • Target

    HLA-ABC

    Alternative Name

    HLA Class I ABC

    Background

    The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells.Synonyms: HLA Class 2 ABC, Human Leukocyte antigen class I ABC, MHC class I ABC, Major Histocompatibility complex class I

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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