IL2 Receptor beta antibody
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- Target See all IL2 Receptor beta (IL2RB) Antibodies
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This IL2 Receptor beta antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Specificity
- This antibody recognises the CD122 cell surface glycoprotein. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. We recommend the use of SM2224LE for this purpose.
- Purification
- Affinity chromatography on Protein G
- Endotoxin Level
- Low Endotoxin
- Immunogen
- Cells from murine IL-2RB+ transformant TART-mBeta. Lymph node (cells from immunised Sprague Dawley rats were fused with cells of the mouse PA1 myeloma cell line.
- Clone
- TM-BETA1
- Isotype
- IgG2b
- Top Product
- Discover our top product IL2RB Primary Antibody
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anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibody
IL2RB Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 1G11C6 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (Internal Region) antibodyIL2RB Reactivity: Mouse, Human, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB Reactivity: Human FACS, IP Host: Mouse Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB Reactivity: Human FACS, IP, Func Host: Mouse Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibody (APC)IL2RB Reactivity: Human FACS Host: Mouse Monoclonal TU27 APC
anti-Interleukin 2 Receptor, beta (IL2RB) (Tyr364) antibodyIL2RB Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (N-Term) antibodyIL2RB Reactivity: Mouse, Human WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB Reactivity: Human WB, FACS Host: Mouse Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibodyIL2RB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Flow Cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody at -20 °C to -70 °C.
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- Target
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Alternative Name
- CD122 / IL2RB (IL2RB Products)
- Background
- CD122 is a 75-85kD molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
- Gene ID
- 16185
- NCBI Accession
- NP_032394
- UniProt
- P16297
- Pathways
- JAK-STAT Signaling, Growth Factor Binding
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