CRYAA antibody

Catalog No. ABIN121144

This Mouse Monoclonal antibody specifically detects CRYAA in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CRYAA antibody (ABIN121144)

Target: CRYAA (Crystallin, alpha A (CRYAA))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRYAA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: C9F2

Product Details anti-CRYAA Antibody

Specificity: The antibody recognizes human , rat and mouse Crystallin-alpha A. Other species not tested.

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human a -Crystallin A protein

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution 1:1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 10 % glycerol and 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CRYAA

Target: CRYAA (Crystallin, alpha A (CRYAA))

Alternative Name: alpha-Crystallin A Chain

Background: Crystallins alpha are composed of two gene products, alpha A and alpha B, for acidic and basic, respectively. crystallins alpha can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha A and alpha B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell.Synonyms: CRYA1, CRYAA, HSPB4, Heat shock protein beta-4

UniProt: P02489

Pathways: M Phase