Adenylate Kinase 3 antibody

Catalog No. ABIN121177

This Mouse Monoclonal antibody specifically detects Adenylate Kinase 3 in WB, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Adenylate Kinase 3 antibody (ABIN121177)

Target: Adenylate Kinase 3 (AK3)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Adenylate Kinase 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: SJB3-36

Product Details anti-Adenylate Kinase 3 Antibody

Specificity: This antibody (clone SJB3-36) has the specificity against AK3.

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human AK3 (adenylaste kinase isozyme 3) purified from E. coli

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution is 1:1,000. Immunohistochemistry (1:100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for Adenylate Kinase 3

Target: Adenylate Kinase 3 (AK3)

Background: Adenylate kinase (AK, adenosine triphosphate-adenosine monophosphate [ATP-AMP] phospho-transferase, EC 2.7.4.3) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (AK1, AK2 and AK3) are characterized in vertebrates. AK1 is present in the cytosol of skeletal muscle, brain, and erythrocyte, while AK2 is localized in the intermembrane space of mitochondria of liver, kidney, spleen and heart. AK3, called GTP:AMP phosphotransferase, exists in the mitochondrial matrix of liver and heart. These isozymes contribute to homeostasis of the adenine nucleotide composition in the cell.Synonyms: AK3L1, AK6, AKL3L, GTP:AMP phosphotransferase mitochondrial

Gene ID: 50808

UniProt: Q9UIJ7

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process