C1QA antibody

Catalog No. ABIN121476

The Sheep Polyclonal anti-C1QA antibody (ABIN121476) specifically detects C1QA in ID. The antibody is reactive with Human samples.

Quick Overview for C1QA antibody (ABIN121476)

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This C1QA antibody is un-conjugated

Application: Immunodiffusion (ID)

Product Details anti-C1QA Antibody

Specificity: This antibody recognises C1q, a sub-component of the C1 complement component.

Purification: Ion exchange chromatography

Immunogen: Human C1q, purified from plasma

Application Details

Application Notes: Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Glycine buffered saline pH 7.4 containing 0.09 % Sodium Azide, 0.1 % EACA, 0.01 % Benzamidine and 1 mM EDTA

Preservative: Sodium azide, Benzamidine, EACA

Precaution of Use: This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Alternative Name: C1q A Subunit

Background: C1q is a sub-component of the first complement component C1, which is formed by the interaction of C1q with the tetramer C1s-C1r-C1r-C1s. C1q is a member of a family of soluble collagen-like proteins and is composed of three basic subunits termed C1QA, C1QB and C1QC which asociate in the proportion 6 A-B subunits (52, 750 Da) and 3 C-C subunits (47,600 Da), to form whole C1q (459,300 Da). C1q binds to IgG and IgM immune complexes, this activates C1r and C1s, which are also bound to C1q and so initiates the classical pathway of complement activation.Synonyms: Complement 1q, Complement C1q

Gene ID: 712

Pathways: Complement System