CSK antibody (C-Term)

Catalog No. ABIN121690

This Goat Polyclonal antibody specifically detects CSK in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for CSK antibody (C-Term) (ABIN121690)

Target: CSK (C-Src tyrosine Kinase (CSK))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This CSK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CSK Antibody

Binding Specificity: C-Term

Specificity: This antibody recognises a cytoplasmic tyrosine kinase designated csk (c-src tyrosine kinase), which downregulates the activity of the c-src oncoprotein.

Purification: Affinity chromatography

Immunogen: Peptide sequence derived from C-terminus of human CSK. AA Sequence:EQLEHIKTHELHL

Application Details

Application Notes: Western Blot: 1/200 - 1/500, this antibody detects a band of approximately 60 kDa and 30 kDa in Jurkat cell lysates, Overnight incubation is recommended with this antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: TRIS buffered saline pH 7.3 containing 0.02 % Sodium Azide and 0.5 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CSK

Target: CSK (C-Src tyrosine Kinase (CSK))

Alternative Name: CSK

Background: Csk is ubiquitously expressed as 2 mRNA species. This antibody detects 2 bands in Western blots of Jurkat cells lysates.Synonyms: C-SRC kinase, Protein-tyrosine kinase CYL, Tyrosine-protein kinase CSK

Gene ID: 1445

Pathways: TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events