HNF4 gamma antibody

Catalog No. ABIN122270

Product Details anti-HNF4 gamma Antibody

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF4 gamma antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with Hepatocyte Nuclear Factor 4 Gamma (HNF4 Gamma/NR2A2) (family: NHR, subfamily: NR2 Hepatocyte NF4-like)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 16-32 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for HNF4 gamma

Target: HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))

Alternative Name: HNF4 gamma / NR2A2 (HNF4G Products)

Synonyms: HNF4G antibody, hnf4gamma antibody, zgc:153265 antibody, NR2A2 antibody, NR2A3 antibody, hepatocyte nuclear factor 4 gamma antibody, hepatocyte nuclear factor 4, gamma antibody, HNF4G antibody, hnf4g antibody, Hnf4g antibody

Background: Hepatocyte nuclear factor 4 gamma (HNF4 gamma) is a NR2 Hepatocyte NF4-Like receptor of relatively unknown function. Although HNF4 gamma is structurally related to HNF4 alpha and is expressed together with HNF 4 Alpha in pancreatic islets, it does not play a major role in the etiology of early onset, autosomal dominant, non insulin-dependent type 2 diabetes or maturity-onset diabetes of the young, MODY1. A pseudogene of HNF4 gamma, located on chromosome 13 (13q14.11 - 13q14.3), has been recently identified using a comparative genomics approach. HNF4 gamma expression has been reported human pancreas, kidney, testis, small intestine, and colon. ESTs have been isolated from human tissue libraries, including cancerous brain and colon, and normal brain,stomach, and liver. Ligand: Saturated and cis-monounsaturated C14-18 fatty acidsSynonyms: Hepatocyte nuclear factor 4-gamma, Nuclear receptor subfamily 2 group A member 2

Gene ID: 3174

UniProt: Q14541

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway