CHRM3 antibody (C-Term)
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- Target See all CHRM3 Antibodies
- CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHRM3 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Reacts with Muscarinic Acetylcholine Receptor M3 (Family: GPCR, Subfamily: Acetylcholine)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Peptide Immunogen Affinity Chromatography.
- Immunogen
- Synthetic peptide - KLH conjugated
- Top Product
- Discover our top product CHRM3 Primary Antibody
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- Application Notes
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 72 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.7 containing 0.01 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))
- Alternative Name
- Muscarinic Acetylcholine Receptor M3 (CHRM3 Products)
- Synonyms
- EGBRS antibody, HM3 antibody, MACHR antibody, Chrm-3 antibody, M3 antibody, M3R antibody, cholinergic receptor muscarinic 3 antibody, cholinergic receptor, muscarinic 3 antibody, cholinergic receptor, muscarinic 3, cardiac antibody, CHRM3 antibody, Chrm3 antibody
- Background
- Muscarinic acetylcholine receptor 3 is an Acetylcholine Receptor that controls smooth muscle contraction by mediating phosphoinositide hydrolysis and Ca2+ mobilization. Activation of this receptor causes secretion in glandular tissues. Mouse studies suggest that the M3 receptor may play a role in appetite stimulation and food intake. Expression of this receptor has been reported in brain, eye, and heart. ESTs have been isolated from brain, colon, fetus, lung, and prostate libraries.Synonyms: CHRM3
- Gene ID
- 1131
- UniProt
- P20309
- Pathways
- Synaptic Membrane
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