NMBR antibody (Cytoplasmic Domain)

Catalog No. ABIN122330

The Rabbit Polyclonal anti-NMBR antibody is suitable to detect NMBR in samples from Human, Mouse and Rat. It has been validated for IHC (p).

Quick Overview for NMBR antibody (Cytoplasmic Domain) (ABIN122330)

Target: NMBR (Neuromedin B Receptor (NMBR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMBR antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NMBR Antibody

Binding Specificity: Cytoplasmic Domain

Specificity: This antibody detects Neuromedin B receptor.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat (Others see 'Immunogen Remarks')Species reactivity (tested):Human

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry on paraffin embedded sections: 16 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for NMBR

Target: NMBR (Neuromedin B Receptor (NMBR))

Alternative Name: Neuromedin B Receptor

Background: The Neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.Synonyms: NMB-R, NMBR

Gene ID: 4829

UniProt: P28336