GPR50 antibody

Catalog No. ABIN122504

The Rabbit Polyclonal anti-GPR50 antibody is suitable to detect GPR50 in samples from Human, Mouse and Rat. It has been validated for IHC (p).

Quick Overview for GPR50 antibody (ABIN122504)

Target: GPR50 (G Protein-Coupled Receptor 50 (GPR50))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR50 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GPR50 Antibody

Specificity: Detects Melatonin-Related Receptor (GPR50) (Family: GPCR, Subfamily: Orphan-A)

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry on paraffin embedded sections: 3-30 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for GPR50

Target: GPR50 (G Protein-Coupled Receptor 50 (GPR50))

Alternative Name: GPR50

Background: Melatonin-related receptor is an Orphan-A GPCR with an unknown ligand. The receptor is related to high-affinity melatonin receptors, yet it is unable to bind the melatonin hormone. Melatonin-related receptor expression has been documented from human CNS tissues, specifically in hypothalamus and pituitary, but not in human peripheral tissues. In animals, expression has also been seen in the CNS, and peripheral tissues including adrenal, heart, kidney, lung, skin, intestine, stomach, and testis.Synonyms: G protein-coupled receptor 50, H9, Melatonin-related receptor

Gene ID: 9248

UniProt: Q13585