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HLA-DR antibody (FITC)

HLA-DR Reactivity: Human FACS, IP, WB Host: Mouse Monoclonal MEM-12 FITC
Pubmed (1 reference)
Catalog No. ABIN125742
$417.45
Plus shipping costs $45.00
100 tests
Shipping to: United States
Delivery in 5 to 7 Business Days
  • Target See all HLA-DR products
    HLA-DR
    Reactivity
    • 128
    • 22
    • 16
    • 15
    • 15
    • 15
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    Human
    Host
    • 105
    • 13
    • 11
    Mouse
    Clonality
    • 122
    • 6
    Monoclonal
    Conjugate
    • 52
    • 13
    • 13
    • 10
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-DR antibody is conjugated to FITC
    Application
    • 111
    • 37
    • 32
    • 20
    • 20
    • 19
    • 17
    • 11
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
    Specificity
    The antibody MEM-12 recognizes common epitope on human HLA-DR which is dependent on the association of alpha and beta chains. DR is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
    Cross-Reactivity (Details)
    Human
    Immunogen
    thymocyte membrane
    Clone
    MEM-12
    Isotype
    IgG1
  • Application Notes
    The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (2 ml) is sufficient for 100 tests.
    Comment

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Reconstitution
    No reconstitution is necessary.
    Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Avoid prolonged exposure to light.
    Storage
    4 °C
    Storage Comment
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." in: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

  • Target
    HLA-DR
    Alternative Name
    HLA-DR (HLA-DR Products)
    Background
    HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system.
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