DAP antibody

Catalog No. ABIN127063

This Rabbit Polyclonal antibody specifically detects DAP in WB and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for DAP antibody (ABIN127063)

Target: DAP (Death-Associated Protein (DAP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DAP Antibody

Specificity: The antibody detects 15 kDa full length DAP1.

Purification: Affinity Chromatography

Immunogen: Synthetic peptide surrounding amino acid 96 of human DAP1.

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol, 1 % BSA and 0.02 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for DAP

Target: DAP (Death-Associated Protein (DAP))

Alternative Name: Death-Associated Protein 1

Background: Death Associated Protein 1 (DAP1) is a 15 kDa protein that functions as a positive mediator of cell death initiated by interferon-gamma. The DAP1 protein is praline-rich and possesses one SH3 binding motif, as well as several consensus protein kinase phosphorylation sites. The protein is localized in the cytoplasma, however the detailed mechanism of its proapoptotic function is unclear.Synonyms: DAP, DAP-1, DAP1

Gene ID: 1611

NCBI Accession: NP_004385

UniProt: P51397

Pathways: Positive Regulation of Endopeptidase Activity, Feeding Behaviour