BMX antibody

Catalog No. ABIN127082

The Rabbit Polyclonal anti-BMX antibody is suitable to detect BMX in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for BMX antibody (ABIN127082)

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMX Antibody

Specificity: The antibody recognizes 76 kDa Etk.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide surrounding amino acid 43 of human Etk

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for BMX

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Alternative Name: BMX

Background: Etk is a member of the Bruton's tyrosine kinase family. Etk is expressed in a variety of hematopoietic, epithelial and endothelial cells. It participates in multiple signal transduction pathways. Phosphorylation of tyrosine 566 by Src kinase is required for activation of Etk in vivo. In endothelial and epithelial cells, Etk is regulated by FAK through phosphorylation at tyrosine 40.Synonyms: Bone marrow tyrosine kinase gene in chromosome X protein, Cytoplasmic tyrosine-protein kinase BMX, ETK, Epithelial and endothelial tyrosine kinase, NTK38

Gene ID: 660

NCBI Accession: NP_001712

UniProt: P51813