BCL3 antibody

Catalog No. ABIN127088

The Rabbit Polyclonal anti-BCL3 antibody has been validated for WB, IP and IHC (p). It is suitable to detect BCL3 in samples from Human, Mouse and Rat.

Quick Overview for BCL3 antibody (ABIN127088)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BCL3 Antibody

Specificity: Detects 55-60 kDa Bcl-3.

Purification: Affinity Chromatography on Protein G.

Immunogen: Synthetic peptide surrounding amino acid 424 of human Bcl-3.

Application Details

Application Notes: Western Blot: 2-4 μg/mL. Immunoprecipation: 10-20 μg/mL. Immunohistochemistry: 20-40 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA, and 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C to -70 °C.

Target Details for BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Alternative Name: Bcl-3

Background: Bcl-3, a proto-oncogene, is believed to be involved in certain human B cell leukemias. It encodes a protein that functions as an IκB-like molecule for native NFκB, but is specific for the p50 subunit of NFκB.Synonyms: B-cell lymphoma 3-encoded protein, BCL3, BCL4, D19S37

Gene ID: 602

NCBI Accession: NP_005169

UniProt: P20749

Pathways: NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus