BCL3 antibody (Middle Region)

Catalog No. ABIN950634

The Rabbit Polyclonal anti-BCL3 antibody (ABIN950634) specifically detects BCL3 in WB, IF, FACS, IHC (p) and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for BCL3 antibody (Middle Region) (ABIN950634)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-BCL3 Antibody

Binding Specificity: AA 248-277, Middle Region

Specificity: This antibody reacts to Bcl-3.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 248~277 amino acids from the Center region of human BCL3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Alternative Name: Bcl-3

Background: BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.Synonyms: B-cell lymphoma 3-encoded protein, BCL3, BCL4, D19S37

Gene ID: 602

NCBI Accession: NP_005169

Pathways: NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus