CYR61
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
3C11
unconjugated
Application Notes
The antibody can be used for Western blotting (0.5-4 μg/mL). Jurkat cell lysate and mousesmall intestine tissue lysate can be used as positive controls. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Cyr61 is a member of angiogenic and vasculogenic regulators designated CCN proteins, which includes CTGF, Cyr61 homolog, Fisp2. Cyr61 functions as an angiogenic inducer, stimulating cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Elevated expression of Cyr61 is observed during vessel growth, wound healing and chondrocyte differentiation.Synonyms: CCN family member 1, CCN1, Cysteine-rich angiogenic inducer 61, GIG1, IBP10, IGF-binding protein 10, IGFBP10, Insulin-like growth factor-binding protein 10