FANCE antibody (AA 1-13)
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- Target See all FANCE Antibodies
- FANCE (Fanconi Anemia, Complementation Group E (FANCE))
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Binding Specificity
- AA 1-13
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FANCE antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Supplier Product No.
- 600-401-673
- Supplier
- Rockland
- Purpose
- FANCE Antibody
- Characteristics
- Synonyms: rabbit anti-FANCE antibody, FANC-E, FANC E, FACE antibody, FAE antibody, Fanconi anemia group E protein, Fanconi anemia complementation group E antibody
- Purification
- This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
- Sterility
- Sterile filtered
- Immunogen
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-13 of Human FANCE. This Fanconi anemia protein promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage. LocusLink ID 2178, SwissProt accession number Q9HB96
Immunogen Type: Conjugated Peptide
- Isotype
- IgG
- Top Product
- Discover our top product FANCE Primary Antibody
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- Application Notes
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Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.
Western Blot Dilution: 1:500- 1:2,000
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Expiry Date
- 12 months
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- Target
- FANCE (Fanconi Anemia, Complementation Group E (FANCE))
- Alternative Name
- FANCE (FANCE Products)
- Background
- Background: Fanconi anemia group E protein (FANCE) is part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. It is required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.
- Gene ID
- 2178
- NCBI Accession
- NP_068741
- UniProt
- Q9HB96
- Pathways
- DNA Damage Repair
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