BCL2L1 antibody (PE)

Catalog No. ABIN135024

Cited in 2+ publications. The PE-conjugated Mouse Monoclonal anti-BCL2L1 antibody (Clone 7B2-5) (ABIN135024) specifically detects BCL2L1 in FACS. The antibody is reactive with Human, Rat, Mouse and Rhesus Monkey samples.

Quick Overview for BCL2L1 antibody (PE) (ABIN135024)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivity: Human, Rat, Mouse, Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL2L1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 7B2-5

Product Details anti-BCL2L1 Antibody (PE)

Purpose: Mouse Anti-Bcl-xL-PE

Specificity: Human/Mouse/Rat/Rhesus Bcl-xL

Characteristics: PE Anti-Bcl-xL antibody for use in flow cytometry assays.

Immunogen: Recombinant human Bcl-xS

Isotype: IgG3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide and a stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

References for anti-BCL2L1 antibody (PE) (ABIN135024)

Urbanska, Lanitis, Poussin, Lynn, Gavin, Kelderman, Yu, Scholler, Powell: "A universal strategy for adoptive immunotherapy of cancer through use of a novel T cell antigen receptor." in: Cancer research, (2012) (PubMed).

Gottschalk, Boise, Oltvai, Accavitti, Korsmeyer, Quintáns, Thompson: "The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated." in: Cell death and differentiation, Vol. 3, Issue 1, pp. 113-8, (2006) (PubMed).

Target Details for BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Alternative Name: Bcl-xL

Background:

Description: Mouse Anti-Bcl-xL-PE

NCBI_Official_Symbol: BCL2L1, Bcl2l1, Bcl2l1, BCL2L1

Synoynms: Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1

Gene ID: 598, 12048, 24888

UniProt: Q07817

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling