CD40 Ligand antibody

Catalog No. ABIN135219

The Hamster Monoclonal anti-CD40 Ligand antibody (Clone MR1) (ABIN135219) specifically detects CD40 Ligand in FACS, IP, ELISA, BR and IHC (fro). The antibody is reactive with Mouse samples.

Quick Overview for CD40 Ligand antibody (ABIN135219)

Target: CD40 Ligand (CD40LG)

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD40 Ligand antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: MR1

Product Details anti-CD40 Ligand Antibody

Purpose: Hamster Anti-Mouse CD154-LE/AF

Specificity: Mouse CD154, Mr 39 kDa

Characteristics: Low Endotoxin/Azide Free Anti-Mouse CD154 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, and blocking assays.

Endotoxin Level: Low Endotoxin

Immunogen: Activated mouse Th1 clone D1.6

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for CD40 Ligand

Target: CD40 Ligand (CD40LG)

Alternative Name: CD154

Background: CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporin-sensitive.

Gene ID: 21947

UniProt: P27548

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints