CD69 antibody

Catalog No. ABIN135258

The Hamster Monoclonal anti-CD69 antibody (Clone H1-2F3) (ABIN135258) specifically detects CD69 in FACS, IP, IHC (fro), CoSt and Act. The antibody is reactive with Mouse samples.

Quick Overview for CD69 antibody (ABIN135258)

Target: CD69

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD69 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Co-Stimulation (CoSt), Activation (Act)

Clone: H1-2F3

Product Details anti-CD69 Antibody

Purpose: Hamster Anti-Mouse CD69-LE/AF

Specificity: Mouse CD69, Mr 85 kDa (unreduced)

Characteristics: Low Endotoxin/Azide Free Anti-Mouse CD69 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, costimulation, and activation assays.

Endotoxin Level: Low Endotoxin

Immunogen: Mouse dendritic epidermal cell line Y245

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for CD69

Target: CD69

Alternative Name: CD69

Background: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly (within 2 hours) upregulated upon activation of T, B and NK cells, and neutrophils.4 Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.

Gene ID: 12515

UniProt: P37217