NK-1.1/CD161c antibody

Catalog No. ABIN135344

The Mouse Monoclonal anti-NK-1.1/CD161c antibody is suitable to detect NK-1.1/CD161c in samples from Mouse. It has been validated for FACS, IP, IHC, BR, Dep, Act and CMCD.

Quick Overview for NK-1.1/CD161c antibody (ABIN135344)

Target: NK-1.1/CD161c (NK-1.1)

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NK-1.1/CD161c antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Blocking Reagent (BR), Depletion (Dep), Activation (Act), Complement Mediated Cell Depletion (CMCD)

Clone: PK136

Product Details anti-NK-1.1/CD161c Antibody

Purpose: Mouse Anti-Mouse NK1.1-LE/AF

Specificity: Mouse NK1.1, Mr 39 kDa

Characteristics: Low Endotoxin/Azide Free Anti-Mouse NK1.1 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, depletion, CMCD, blocking, and activation assays.

Endotoxin Level: Low Endotoxin

Immunogen: CE mouse spleen enriched for NK-1+ cells and bone marrow cells

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for NK-1.1/CD161c

Target: NK-1.1/CD161c (NK-1.1)

Alternative Name: NK1.1

Background: NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL, NZB). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.

Gene ID: 17059

UniProt: P27814