ITGA4 antibody

Catalog No. ABIN135383

The Rat Monoclonal anti-ITGA4 antibody has been validated for FACS. It is suitable to detect ITGA4 in samples from Mouse.

Quick Overview for ITGA4 antibody (ABIN135383)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: DATK32

Product Details anti-ITGA4 Antibody

Specificity: Mouse LPAM-1

Characteristics: Rat Anti-Mouse LPAM-1-LE/AF

Endotoxin Level: Low endotoxin

Immunogen: AKR/Cum mouse T lymphoma cell line TK-1

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , Block - Reported in literature , IP - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells BIOT conjugate 1 g/106 cells PE conjugate 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Comment:

Blockade of binding to cell adhesion molecules, Induction of homotypic cellular aggregation

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of PBS

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: -20 °C

Storage Comment: Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Background: The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin 47, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The 47 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.

Pathways: Integrin Complex